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There have been no reported safety concerns, no significant drug-related adverse events, no deaths, and no adverse events leading to discontinuation of a study [8, 9, 10, 11, 12, 13, 14, 15]

Doesn't get better than that

Race/Ethnicity - According to the CDC older African Americans are twice more likely to have dementia than whites

Polyphenols are one of the largest and most important classes of bioactive chemicals of plants, with two or more hydroxyl groups in the benzene ring [186]

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Remember, while patches can be helpful, maintaining a consistent skincare routine and consulting with a dermatologist for persistent issues is always recommended.