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AOD-9604 also inhibits lipogenesis, the synthesis of new fat, adding a second metabolic angle

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[1] [2] These occur because liraglutide slows gastric emptying as part of its mechanism of action, which contributes to feelings of satiety and supports weight loss

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Meta-analyses show that semaglutide increases the likelihood of discontinuing treatment (relative risk 1.67, 95% CI 1.27-2.21), primarily due to gastrointestinal adverse events like nausea, vomiting, and diarrhea

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