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Little is known about whether its safe to use milk thistle during pregnancy or while breastfeeding

Corcoran, A

3, 2014, pp

Follow safe practices choose quality products, stick to recommended doses, and consult your healthcare provider if needed

In a mouse model of AD, probiotic treatment with Lactobacillus and Bifidobacterium strains improved cognitive function and reduced amyloid-beta deposition, supporting a neuroprotective role of gut microbiota modulation ( 3.6.4.2 Dietary interventions Stroke not only causes direct brain injury but also induces systemic changes including gut dysbiosis and impaired intestinal barrier function, which can contribute to infection risk and influence stroke severity and recovery

It would take randomized, placebo-controlled trials in humans, ideally several, run in more than one country and by groups without a financial stake in the answer, measuring a pre-specified cognitive outcome rather than a grab-bag of secondary ones