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in astrocytes, it is metabolized to the neuroprotective metabolite KYNA

Nocton, J

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The antibody used in the assay binds specifically to the C-terminal portion of GLP-1 and to both amidated and non-amidated forms, and GLP-1 (736) amide was used as standard and to prepare 125 I radiolabeled GLP-1

The importance of gut microbiota in early life and brain development is demonstrated by animal studies showing that maternal separation of neonates does not only lead to a dysbiotic state of the microbiota that persists into adulthood, but also results in long-term cognitive and behavioral deficits (159)

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