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Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion

GLP-1 RAs were significantly associated with gastrointestinal AEs, and the association was further attributed to liraglutide, dulaglutide, and semaglutide

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Semaglutide downregulates the transcription factor PPARG, thereby reducing its inhibition of the downstream molecule ACSL1, leading to increased ACSL1 expression and promoting M1 polarization, ultimately enhancing the anti-tumor effects [95]

Humans express two monoamine oxidase encoding genes identified as MAOA and MAOB