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The hepatocyte growth factor (HGF) receptor, Met, has been implicated in HNSCC tumorigenesis and EGFR inhibitor resistance

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87 l of solvent B (15% NH 4 HCO 3 in water) was added, vortexed, and kept on dry ice for 20 min to neutralize

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Genetic variants that alter the function of a therapeutic receptor are known to influence drug response through several mechanisms

Las limitaciones actuales de la investigacin incluyen la ausencia de ensayos clnicos aleatorizados de gran envergadura en humanos, una comprensin an parcial de los mecanismos moleculares precisos y una falta de datos farmacocinticos detallados en humanos