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Abstract Thiazides, thiazide-like and loop diuretics are commonly prescribed to manage hypertension and heart failure

The Journal of Clinical Investigation

Effects typically last 1 to 4 weeks depending on your baseline B12 levels

These include standardizing vitamin D assays, better characterizing baseline vitamin D status, and accounting for genetic factors that influence vitamin D metabolism

Its primary role is to neutralize free radicals, protect cells from oxidative stress, and support the immune system

A report from the Framingham Offspring Study of 2,999 adults found the following average daily B12 intakes, including fortified foods and supplements (Tucker, 2000): Age 26-49: 8.9 g Age 50-64: 8.7 g Age 65-83: 8.5 g A 2015-2016 National Health and Nutrition Examination Survey of over 4,500 adults 60 years and older found the following average daily B12 intakes (USDA NHANES, 2019): Male non-supplement users (68% of men): 4.5 g Male supplement users: 5.3 g from food plus 326 g from supplements Female non-supplement users (63% of women): 3.6 g Female supplement users: 3.8 g from food plus 520 g from supplements European Food Safety Authoritys Recommendations In 2015, the EFSA released recommendations for B12 intake across Europe