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In the UK, typical oral doses for dietary deficiency are 50-150 micrograms daily, with higher doses (1000-2000 micrograms) generally reserved for clinical situations under healthcare supervision

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In clinical trials, 100% of healthy volunteers experienced this chromaturia with administration of 5g hydroxocobalamin with other common effects including erythema, rash (predominantly acneiform appearance) and increased blood pressure

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Improving strength, aerobic performance, and muscle endurance [2, 3]

Stressful routines shorten them