Certain conditions may blunt or impede therapeutic response to methylcobalamin therapy
Liver fibrosis is determined by a proliferation of liver stroma cells and by alterations of the liver vasculature
It is commonly used as a depigmenting agent
Instead, the results indicate that therapeutic exposure, reflected by the maximum dose patients attained, may better capture the mechanisms underlying long-term cardiovascular protection
However, clinicians should consider the possibility of NAFLD in individuals with abnormal liver function tests or incidental findings of hepatic steatosis on imaging, particularly if metabolic risk factors are present
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