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Description

GLP-1RAs have been combined with glucose-dependent insulinotropic agonism, as well as glucagon agonism or amylin analogues to further enhance their metabolic benefits

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These effects are generally mild to moderate in severity and are most common during escalation from lower starting doses

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Physician 102 , 603612 (2020)

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Despite this brief duration, GLP-1 exerts significant physiological effects on glucose homeostasis, appetite regulation, and gastric emptying

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There is no way to predict without testing

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If you are losing weight at a satisfactory rate on 8mg with minimal side effects, staying at 8mg is a perfectly valid choice

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