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Several reports showed controversy about the expression of the IGF family and their connection to prostate cancer risk due to the high degree of heterogeneity among prostate tumors, sampling bias, and evaluation techniques
Public awareness campaigns must demystify GLP-1s: educate via TV, social media, and clinics that they're not "magic pens" but supervised therapies
In addition to hydrolases, lysosomes can act as a store for various ions
J Mol Endocrinol 2013
Obesity-associated adipose tissue thus functions as an inflammatory endocrine organ, particularly in visceral tissue producing TNF-, IL-6, IL-1, Monocyte chemoattractant Protein 1 (MCP-1, which is associated with tamoxifen resistance), and leptin while reducing adiponectin (an anti-inflammatory adipokine) levels, thereby promoting chronic low-grade inflammation, insulin resistance, and tumor-promoting signaling pathways
10.1038/nature13701 181 LiQ.AtochinD.KashiwagiS.EarleJ.WangA.MandevilleE.et al (2013)
