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Pharmacodynamics (Effect)This section has been translated automatically

Results Female sex promotes statin-induced glucose intolerance and reduced muscle strength in the mouse We treated cohorts of male and female C57BL/6 J mice (aged 10 weeks) with a chow diet without or with simvastatin (equivalent to human dose of 80 mg/day

Crucially, there is no established evidence base for efficacy at low doses specifically for inflammation, and the dose-response relationship for anti-inflammatory effects is unknown

While Accutane therapy can be life-changing for people with severe acne, its strength comes with trade-offs

Available online at: 49 FaZ.ZhangP.HuangF.LiP.ZhangR.XuR.et al (2010)