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The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis
Reimer J, et al
Conclusions Unstable iron deposits within cells lead to an unbalanced redox state, causing a type of cell death known as ferroptosis which differs from other types of death
It can activate the division and migration of epidermal cells, promote the repair and regeneration of damaged tissues, and accelerate wound healing
This article outlines the steps of the proposed integrative neurogenomics workflow, discussing its advantages and limitations, and presents highlights from an illustrative case intended as a potential reference model to establish the foundation for a new standard of personalized genomic medicine in neurodegeneration
Nat Rev Cancer 17(9):52842 Li M, Yang Z, Vollmer LL, Gao Y, Fu Y, Liu C et al (2015) AMDE-1 is a dual function chemical for autophagy activation and inhibition
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