BPC-157 (Body Protection Compound-157) is a synthetic peptide composed of 15 amino acids (sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val), with a molecular weight of approximately 1,419 Daltons
The pharmaceutical pen formulations of semaglutide and tirzepatide have slightly different guidelines because they use different preservative systems, but the underlying peptide stability is comparable
However, people on specific medicationsparticularly chemotherapy agents or medications metabolized by glutathioneshould consult a provider before starting supplementation
A recent phase IIb RCT (CENTAUR) showed that cenicriviroc had no efficacy on NASH resolution but improved at least one fibrosis stage at 1 year of treatment but not after 2 years
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Bottom line: Wegovy and compounded semaglutide both contain the same GLP-1
