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Cell viability was assessed 3 days after treatment with FOXO4-DRI at 0, 12.5, 25, 50, and 100 M, respectively, using the Cell Counting Kit-8 (CCK-8) Assay (Dojindo, Rockville, MD, United States)

Clinical data shows the combination produces significantly greater weight loss than either agent alone

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We found no significant effect of treatment on survival to adulthood for either exposure age (Supplementary Fig

GHK-Cu is a copper-binding peptide with various biochemical effects