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7 Department of Reproductive Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, Peoples Republic of China *These authors contributed equally to this work Correspondence: Lei Zhang, Department of Endocrinology and Metabolism, Binzhou Medical University Hospital, Binzhou, Shandong, Peoples Republic of China, Email [email protected] Background: GLP-1 receptor agonists (GLP-1 RA) have been proven to treat several metabolic diseases