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Increased Co-Expression of PSMA2 and GLP-1 Receptor in Cervical Cancer Models in Type 2 Diabetes Attenuated by Exendin-4: A Translational Case-Control Study

287,288 This binding initiates typical GPCR signaling, leading to G protein activation and increased intracellular cAMP

The thought is that the GLP-1 agonists mechanism of action can lead to pancreatic cell hyperplasia (since the GLP-1 receptors are in the islet beta cells and exocrine duct cells), leading to a back up in pressureand you got it, inflammation

Why the Obesity GLP-1 Market is Growing

A: Research shows mixed results

doi: 10.1093/cvr/cvz323 109 SharmaAVermaS