That caution is the point
[2] mhra.gov.uk)
Yes, surgery is a one-time investment, while GLP-1s can cost $10,000+ yearly, making surgery more cost-effective over time
IGF-1 LR3 and insulin secretagogues should not be combined without close blood glucose monitoring due to additive hypoglycemic risk: IGF-1 LR3 reduces glucose uptake in fat cells while insulin secretagogues drive glucose into muscle, and combining both without monitoring can produce dangerous blood sugar drops
Yes, and many clinicians intentionally prescribe both peptides concurrently for patients with combined goals
Pardali EC, Gkouvi A, Gkouskou KK, Manolakis AC, Tsigalou C, Goulis DG et al (2025) Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases