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In summary, convergent evidence from both preclinical and clinical research underscores the capacity of GLP-1RAs to interact with neural circuits that govern reinforcement and motivation, networks that are also targeted by drugs of abuse

doi: 10.1007/s10654-018-0422-8

Given that the GLP-1 receptor is expressed in metastatic prostate cancer (PCa) tissue, there is growing interest in the potential impact of these agents on PCa outcomes