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Despite being discovered first, it received less clinical attention for decades because early research suggested that GIP signaling was impaired in type 2 diabetes, making it seem like an unlikely therapeutic target

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Finally, the complex reactions of FSP1 are involved in the regulation of ferroptosis, especially the catalytic products including ubiquinol, reduced hydroquinone (VKH2), and 6-hydroxy-FAD that can suppress the ferroptosis

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