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In this approach, CAT-containing samples are introduced to defined H 2 O 2 concentrations in phosphate buffer (pH 7.0), with absorbance decline rates proportional to enzymatic activity

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It is gentler but is only appropriate where a clinician has advised the subcutaneous route

Ott Email: [email protected] ORCID iD: 0000-0001-7837-3315 SPIN-code: 2232-9914 MD Russian Federation, Saint Petersburg Lyudmila S

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Follow-up Re-check metabolic markers and IGF-1 after 6-8 weeks, with earlier review if GI symptoms, glucose symptoms, or fluid retention occur