These studies highlight the importance of continued treatment for sustained success
If someone loses 40 pounds but a large chunk of that is lean mass, they may end up smaller but weaker, flatter, more tired, and more prone to regain once appetite comes back or the medication changes
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Preclinical and translational studies provide plausible explanations for these observed cardiovascular effects
Stopping the drug needs to be done slowly under the guidance of your doctor
Avoiding high-fat, high-fiber, and high-sugar foods during week one of each dose escalation can also minimize intestinal distress, though moderate soluble fiber (oatmeal, chia seeds, psyllium) later in your cycle may actually shorten symptom duration