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A post hoc analysis of the phase IIb trial showed that tirzepatide was associated with a reduction in the level of high-sensitivity ICAM-1, CRP, and YKL-40 after 26 weeks of treatment in a dose-dependent manner [83, 103]

Patients should be aware that tirzepatide may affect the absorption of oral medications, including oral contraceptives

Interested in gut peptides, in 1980 Lund found a gene for the glucagon precursor in Goodman's library (Lund, Goodman, Dee, Habenerr)

Aon found only one-fifth of employers have a lifestyle or behavior management program to support employees taking GLP-1s

PPG neurons of the lower brain stem and their role in brain GLP-1 receptor activation

Improve insulin sensitivity, lowering fat storage