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The departure of Commissioner Marty Makary in May 2026 and the appointment of Acting Commissioner Kyle Diamantas have introduced fresh questions about continuity and regulatory philosophy at an agency that was already under intense scrutiny

Most studies have found a decrease in GLP-1 secretion in obese individuals [92], and some studies have found no difference in GLP-1 levels between obese and normal-weight controls [93]

clinicians should cut maintenance rates roughly in half and monitor for neurologic symptoms

Lactobacillus reuteri mitigates hepatic ischemia/reperfusion injury by modulating gut microbiota and metabolism through the Nrf2/HO-1 signaling