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CYP2D6 regulates MDMA O-demethylenation leading to the formation of 3,4-dihydroxymethamphetamine (HHMA) and the 4-hydroxylation of methamphetamine (pholedrine) (see Figures 1 and 2)

Virani SS, Newby LK, Arnold SV, et al

So, the big scary side effects that we keep hearing about, again, dosing and management issue

An additional 272 family derivatives have also been served

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One animal study of cataracts showed its ability to reduce levels of glycated lens proteins, prevent the loss of protective enzymes, and, ultimately, to delay the clouding of the lens