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To evaluate Dihexas ability to cross the BBB and accumulate in brain regions, rats were fitted with carotid cannulas and infused with a mixture of [H]Dihexa (10 Ci) and [C]inulin (2 Ci), a vascular space marker, in 100 l of isotonic saline

M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice

Expectations should emphasize body composition changes, metabolic improvements (blood glucose, lipids, inflammation markers), and behavioral shifts rather than dramatic weight reduction