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The review further distinguishes between established outcome benefits (CVD, CKD, and OSA) and conditions still under investigation (neurodegeneration, arthritis, and some liver endpoints)

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doi: 10.1001/jama.2010.263 204

Diabetes 56:17831791 Krauss S, Zhang CY, Scorrano L et al (2003) Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction

The path to restorative sleep is individual, but the principles that guide it are consistent