Potential side effects are typically mild but can include [generic side effects such as nausea, headache, etc.], depending on individual tolerance and dosage
Vitamin B12 also may be involved in maintaining sulfhydryl (SH) groups in the reduced form required by many SH-activated enzyme systems
The absorption of vitamin B12 is fraught with hurdles: In the stomach, vitamin B12 needs to bind with a protein called Intrinsic Factor to absorb, plus sufficient acid to release it from protein foods
A colourless or green-tinged solution indicates the complex has been disrupted rather than simply diluted, and visible absorption spectrophotometry around 500-600 nm is the standard bench check on complex integrity
Experienced users and clinic protocols recommend taking breaks
Slightly swipe onto fingertips and gently massage from the inside to the outside of the eye area for absorption