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27 Several, non-enzymatic cofactors like TAFs, mediators, and numerous enzymatic cofactors like the histone-modifying cofactors (histone deacetylase, histone acetyltransferase, histone methyltransferase, histone demethylase) and ATP-dependent chromatin-remodeling cofactors (SWI/SNF, ISWI, Mi-2/NuRD, and INO80/SWR1 families) have been discovered since

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Phenotypic differentiation of neutrophils is regulated by NK cells, which can promote neutrophil polarization toward the N1 phenotype through an IFN--dependent mechanism (119)