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Clin Chem 1998;44(1):148-54

SGLT2i prescriptions showed high model reliability (63.7%83.1%) and were consistently associated with key markers of cardiorenal vulnerability, such as reduced eGFR, intermediate HbA1c levels (5.5%8.1%), history of atherosclerotic cardiovascular disease, and heart failure

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Finally, among GLP-1 RA, the Effect of Efpeglenatide on Cardiovascular Outcomes (AMPLITUDE-O) trial demonstrated a beneficial effect of weekly efpeglenatide on MACE and on a composite kidney outcome (decrease in kidney function or severe albuminuria) [247]