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One of the most promising drug classes in recent years is GLP-1 receptor agonists, including semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro).These medications have revolutionized weight loss and diabetes management, with additional potential benefits in reducing risks for conditions like sleep apnea, cardiovascular disease, and even alcohol dependence

When it first appeared, the drug won a nod to prescribe for obese patients with an initial body mass index of 30kg/ or more or overweight adult patients with a BMI from 27kg/ to 30kg/ having one or more weight-related comorbidities

People with obesity or overweight (without T2DM) showed significant weight loss

A study design examining both covers axes that neither reaches alone

4, Supplementary Fig

There are many possible causes of gallbladder issues, including gallbladder disease, gallstones, and other rarer conditions which impair gallbladder functioning