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If you start feeling full while eating, stop

When Wegovy is introduced, its gastrointestinal effects may overlap with existing post-cholecystectomy symptoms, potentially making digestive side effects more noticeable or troublesome

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Dose ceiling: The MHRA has now approved a 7.2mg dose in the UK (January 2026), which produces an average weight loss of 20.7%

Most patients beginning semaglutide therapy experience their first side effects between days three and seven of starting treatment, with nausea representing the most frequent initial reaction

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