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The rationale is twofold

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Due to their reduced extraction time, energy consumption, and use of harmful organic solvents, as well as their higher extraction yields for recovering antioxidant compounds from food and medicinal plants, the aforementioned non-conventional methods have the potential to replace or enhance existing extraction methods [66]

doi:10.3390/ijerph9113934

Our in vitro results demonstrate that targeting PGC-1 significantly impairs mitochondrial function and disrupts energy metabolism, affecting critical pathways such as glycolysis and the citric acid cycle, as well as altering mRNA nuclear export

One key player is somatostatin, a hormone that suppresses growth hormone release