If fatigue worsens specifically in the 24 to 72 hours after your injection and then improves, it is likely medication-related
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9,12 Additionally, GLP-1RAs activate nitric oxide (NO) synthase expressed in Schlemms canal and the trabecular meshwork, increasing NO production to reduce trabecular meshwork contraction, improving aqueous outflow
doi:10.1080/00325481.2020.1788340.
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A significant limitation of the current clinical evidence is its reliance on post-hoc analyses of cardiovascular outcome trials and large-scale retrospective studies