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135 Similarly, a trial in 63 healthy adults with self-reported sleep problems found 14 mg saffron extract twice daily for 28 days led to greater improvement in sleep quality scores than placebo

Consult a doctor in the event of feeling unwell or having adverse effects related to the contact with the substance

The McKenzie method uses specific extension exercises to centralize pain

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Study exclusion criteria may have selected patients at lower risk of overdose, and substantial loss to follow-up (approximately 80%) also may have biased estimates

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