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So they fit well in our bodys complex machinery

BRCA1, which regulates cell cycle progression, DNA damage signalling and repair, and maintenance of genomic integrity, interacts with NRF2 either directly, through its ETGE motif, preventing KEAP1-dependent ubiquitination of NRF2 and protecting cells against OS, or indirectly, through the interaction with CBP or with c-Myc [186]

they hunt down the root cause

A review of over 300 casecontrol and cohort studied used final height as an indication of GHIGF-1 action and found that individuals over 175 cm have a 20% higher chance of developing prostate cancer, a 22 and 2060% higher chance of breast and colorectal cancers, respectively, when compared with individuals below 160 cm (278, 279)

Lee, S., Manjunatha, D