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The SDS gene is located on chromosome 12q24.13 and is composed of 8 exons that encode a protein of 328 amino acids

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In summary, we conclude that the glutathione system is the dominant mediator of antioxidative electron flux under pronounced pro-oxidative conditions across different eukaryotic kingdoms

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Consistent with our microarray data, we found a significant increase in the expression of Fasn , which encodes fatty acid synthetase, and Ppara , which encodes PPAR, the master transcriptional regulator for -oxidation, in adipocytes lacking GPR146 (Fig