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The MS1, MS2, and MS3 files were extracted from RAW files using RawConverter (v1.2.0.1, available at uploaded to Integrated Proteomics Pipeline (IP2) and searched using the ProLuCID algorithm with a reverse concatenated version of the Mouse UniProt database (release-2024-03)
Across the SLD spectrum, GLP-1 RAs demonstrated modest but directionally consistent improvements in liver enzyme profiles (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]), with 4 of the 7 ALT outcome estimates showing significant reductions, and 4 of the 9 AST outcome estimates showing significant reductions
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Kidney disease: High B12 levels can result from damage to cells, which releases substances like hemoglobin and B vitamins into the blood
doi: 10.1097/00005792-198507000-00007
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