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Its defining pharmacological characteristic relative to its predecessors (GHRP-2, GHRP-6) is its selectivity: at doses exceeding 200-fold the GH-release ED, ipamorelin does not stimulate significant release of adrenocorticotropic hormone (ACTH), cortisol, prolactin, FSH, LH, or TSH, in animal studies

It enhances biochemical signaling for collagen and glycosaminoglycan production, recruits immune and endothelial cells to injury sites, and promotes remodeling of connective tissue

and SURMOUNT-MMO (NCT05556512), involving individuals who are overweight or obese

The good news is that this type of hair loss is usually reversible once nutritional status stabilizes