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The before-and-after for this group often centers on body composition rather than total pounds, clothes fitting better, more defined musculature as fat recedes, and a visible transformation in the face, neck, and midsection

However, development was discontinued in 2007 after the largest Phase IIb trial failed to demonstrate statistically significant weight loss compared to placebo

doi: 10.3390/microorganisms7100456 37 VallianouNStratigouTChristodoulatosGSTsigalouCDalamagaM

The composition-of-matter patent expiring in 2023 does not extend their ability to compound beyond that 60-day window

[DOI] [PubMed] [Google Scholar] 162.Shore S.A., Terry R.D., Flynt L., Xu A., Hug C