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409 In animal experiments, LPS stimulation resulted in excessive activation of platelets, leading to a significant increase in adhesion, aggregation, secretion, and diffusion on fibrinogen, as well as the expression of platelet membrane glycoproteins

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doi: 10.1093/rheumatology/31.4.281

Skipping dose steps dramatically increases the risk and severity of adverse events

Retatrutide is better described as a triple agonist