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Possibly, but in clinical studies of semaglutide involving thousands of people, dry mouth wasnt a documented side effect

Measurement of food intake, body weight, liver, and heart weight To evaluate and compare the anti-obesity effect of semaglutide, tirzepatide, and retatrutide in MC4R KO mice, we repeatedly administered vehicle (saline) to normal C57BL/6 J and MC4R KO mice, semaglutide (0.1 mg/kg), tirzepatide (0.05 mg/kg), and retatrutide (0.05 mg/kg) to MC4R KO mice

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This treatments is recommended 2-3 times every 6 months

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a mitochondrial manganese superoxide dismutase (SOD2)