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Additionally, the reduction in -amyloid (140) levels in animals supplemented with PXN HIGH and CAF HIGH suggests a potential mechanism for the cognitive benefits observed

Food and Drug Administration (FDA) Breakthrough Therapy Designation for both indications and FDA Rare Pediatric Disease Designation in congenital HI

May 5, 2017

DMR remains an investigational therapy and does not yet have FDA approval

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In in vitro models, LPS disrupts the barrier with decreased TEER and increased permeability [67]