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Importantly, GLP-1 therapies have not been associated with an increased risk of pancreatitis or thyroid cancer in clinical trials

Norris SMP, Childers E, Pool R, editors

Liraglutide reduces cns activation in response to visual food cues only after short-term treatment in patients with type 2 diabetes

The magnitude of weight loss with semaglutide and tirzepatide places pharmacotherapy into a category that previously would have only been associated with surgical intervention

GIPR is expressed in adipose tissue, bone, and the central nervous system, particularly in brain regions involved in reward processing and energy homeostasis

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