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This platform enables the functional screening and profiling of compounds that modulate gut hormone secretion and nutrient sensing, accelerating innovation in the treatment of metabolic disorders

Due to the fact that Ozempic promotes delayed gastric emptying, it has been used off-label as a weight loss drug

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More than 330 people tried it and some dropped more than 17 percent of their weight by 24 weeks and 24 percent by 48 weeks

The rationale is elegant: because GLP-1 receptors are enriched in metabolically active brain regions, using GLP-1 as a delivery vehicle allows estrogen to be directed preferentially toward the central nervous system, potentially enhancing its neuroprotective effects while limiting systemic hormonal exposure