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High b12 with injections Have posted before, but need to know a couple of things

PNPO mutations are treated with high doses of P5P (active form), thus providing the active form of B6 without the need for conversion

Recent Findings Clinical trials have proven that the widely used GLP-1 analogues have pleotropic effects beyond those on weight and glucose metabolism and appear to confer favourable cardiovascular and renal outcomes

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If your insurance coverage changes and no longer covers your current formulation, work with your provider to transition to the covered option rather than discontinuing GLP-1 therapy entirely

Lowering the Risk of Heart and Kidney Diseases: They are associated with a reduced risk of cardiovascular events and kidney complications in patients with diabetes