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If nausea continues beyond 4 weeks or worsens despite waiting, it may indicate the need for a dose adjustment, dietary modification, or a different medication approach

In the SUSTAIN 6 trial of subcutaneous once weekly semaglutide, more retinopathy events occurred in the semaglutide group

The Journal of urology, 190(6), 22002205

Berberine is generally well-tolerated at typical doses but can cause gastrointestinal effects like nausea, constipation, or diarrhea in some people

Men with a personal or family history of medullary thyroid carcinoma should not use GLP-1 agonists, regardless of testosterone status

Retrospective analyses indicate a 35% reduction in the risk of end-stage renal disease among lupus nephritis patients treated with GLP-1RAs, suggesting both renal and systemic benefits [405,406,407,408]