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Injection therapy into the plaque with interferon -2b, or verapamil are both successful options that help prevent curvature, possibly improve curvature and may decrease penile pain in the early phase of Peyronies disease

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To validate whether the approach can solubilize proteins from the active zone, the authors introduced TurboID into the endogenous ELKS-1 gene, which encodes a presynaptic active zone protein