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In MIN6B1 cells, cAMP production after extended treatment with exendin-4 and exendin-asp3 was marginally reduced compared to the vehicle (Fig

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Alongside pricing and devices, companies are also investing in patient support programmes to improve adherence

Bottom line: Most side effects are gastrointestinal and can be managed by switching to a more bioavailable format like a liposomal liquid

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The successful readout of Novos SELECT cardiovascular outcomes trial represents a moment of truth for the future trajectory of the obesity market, with profound ramifications beyond Wegovy itself