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Recommended use Its recommended that prescription-only orlistat (120 mg) be taken three times a day, during or within 1 hour after a fat-containing meal ( Typically, significant weight loss occurs only after the medication is taken for at least 2 months, though weight loss can begin in as little as 2 weeks

doi: 10.1186/1472-6963-14-419

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Rudofsky, S